Antimicrobial Resistance

Global AMR strategies exist, but most lack funding and action.

Although 178 countries have antimicrobial resistance (AMR) action plans, only 27% report effective implementation and just 11% have allocated budgets. Resistance to key antibiotics like third-generation cephalosporins and methicillin is rising, and data gaps obscure true trends. Cross-sector coordination and investment are urgently needed.

Insights

Political: Commitments to tackle AMR often lack funding and enforcement, with governance gaps remaining in many regions.

Economic: Rising resistance increases treatment costs, hospital stays, and mortality, with the highest burden in low-resource and fragile health systems.

Social: Low public awareness and poor prescribing practices contribute to antibiotic misuse.

Technological: Global Antimicrobial Resistance and Use Surveillance System (GLASS) offers valuable tools to track AMR, but infrastructure remains weak—particularly in lower-income countries.

Legal: Few countries enforce restrictions on antibiotic misuse in humans, animals, or agriculture, contributing to overuse and under-regulation.

Environmental: Resistant organisms circulate through water, soil, and food chains—linking AMR to broader environmental degradation and climate change.

Reflective Questions

  • How can cross-sector financing models help turn national AMR plans into effective, on-the-ground action?

  • What innovations could strengthen resistance surveillance and promote responsible antimicrobial use across all levels of the health system?

  • How can legal frameworks better connect human, animal, and environmental health to help curb the spread of antimicrobial resistance?

Related Insight Cards

References:

World Health Organization, 2023. Antimicrobial resistance: accelerating national and global responses. WHO strategic and operational priorities to address drug-resistant bacterial infections in the human health sector, 2025–2035. Report by the Director-General. Geneva: World Health Organization. EB154/13. Available at: https://apps.who.int/gb/ebwha/pdf_files/EB154/B154_13-en.pdf

World Health Organization, n.d. Global antimicrobial resistance and use surveillance system (GLASS). The global health observatory [online database]. Geneva: World Health Organization. Available at: https://www.who.int/data/gho/data/themes/topics/global-antimicrobial-resistance-surveillance-system-glass

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